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What is "hepatocyte growth factor receptor"?

Cell surface protein-tyrosine kinase receptors for hepatocyte growth factor. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations of the gene for proto-oncogene proteins c-met are associated with papillary renal carcinoma and other neoplasia.

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