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The meaning of lymphocyte proliferation

Morphologic alteration of small B lymphocytes or
T lymphocytes in culture into large blast-like cells
able to synthesize DNA and RNA and to divide
mitotically. It is induced by interleukins, mitogens
such as phytohemagglutinins, and by specific
antigens. It may also occur in vivo, as in graft
rejection.

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