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Definition of kuru

A prion disease found exclusively among the Fore
linguistic group natives of the highlands of New Guinea.
It is marked by the subacute onset of tremor and ataxia
followed by motor weakness and incontinence. The condition
is associated with ritual cannibalism, and has become rare
since this practice has been discontinued. Pathologic features
include a noninflammatory loss of neurons that is most
prominent in the cerebellum, glial proliferation, and
amyloid plaques.

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